Repeated Assessment of Exercise Capacity under Goal-Oriented Sequential Combination Therapy for Pulmonary Arterial Hypertension
نویسنده
چکیده
Little is known about the effects of sequential combination therapy on exercise capacity in pulmonary arterial hypertension (PAH). We monitored exercise capacity by cardiopulmonary exercise testing (CPX) and observed the benefit of using a peak oxygen uptake (VO2) cut-off of 15 mL/min/kg to guide combination therapy. The patients underwent CPX at baseline and after 3, 6, and 12 months. In patients newly diagnosed with PAH, exercise capacity progressively improved due to sequential combination therapy that was revised according to patients’ peak VO2. Therefore, repeated CPX assessment can provide useful information regarding the effectiveness of goal-oriented treatment for PAH.
منابع مشابه
Circulatory power and ventilatory power over time under goal-oriented sequential combination therapy for pulmonary arterial hypertension
Many therapeutic options are available for patients with pulmonary arterial hypertension (PAH). However, little is known about the effects of sequential combination therapy on exercise capacity. Here we monitored exercise capacity by cardiopulmonary exercise testing (CPX) and observed the benefit of using a peak VO2 cutoff of 15 mL/kg/min to guide combination therapy. Thirty patients newly diag...
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